- Linyi shengming chemical products Co., Ltd
- Linyi shengming chemical products Co., Ltd
Home>Products>Pure Research Chemicals>Etizolam Intermediate Pharmaceutical Products C17H15ClN4S Formula SGS Certificat
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Etizolam Intermediate Pharmaceutical Products C17H15ClN4S Formula SGS Certificat
- Etizolam
853122-18-2
- SGT151
- 10g
- Negotiable
- 1-2days
- Western Union, T/T, MoneyGram
-
Linyi shengming chemical products Co., Ltd2020-07-10 09:46:19
Welcome to my shop! Glad to serve you! Please send your question!
Product Details
| Place of Origin: | china | Supply Ability: | 500kg per month | Packaging Details: | safe and discreet packaging |
| other name: | Etizolam | cas: | 853122-18-2 | Colour: | white |
| shipping: | DHL EMS | Appearance: | Powder | Formula: | C16H13ClN2O |
Product Description
Pure white powder Enterprise Standard Pure Research Chemicals Etizolam Etizola Etizest Powder 52170-72-6
Etizolam Intermediate Pharmaceutical Products C17H15ClN4S Formula SGS Certification
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Product name: Etizolam |
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CAS: 40054-69-1 |
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Appearance:white crystalline powder |
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Purity: 99.8% |
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Usage: For research purpose |
Packing: Aluminum foil bag or as clients requirements
Delivery time: Within 3-5 working days after payment confirmation
Shipping: HK EMS,EUB,UPS,Fedex,DHL,TNT
Payment Terms: Western Union,Money Gram,Bitcoins.
If you need detailed information or have any question, please feel free to contact me, I will give you reply as
soon as possible.
Price
Price Condition :FOB
Delivery Port :shenzhen
Packaging & Delivery
Delivery Lead Time :1-2days
Minimum Order :10g
Supply Ability :1000kg/month
Etizolam (marketed under the brand name Etilaam, Etizola, Sedekopan, Etizest, Pasaden or Depas) is
a benzodiazepine analog. The etizolam molecule differs from a benzodiazepine in that the benzene
ring has been replaced by a thiophene ring and triazole ring has been fused, making the drug a
thienotriazolodiazepine. It possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and
skeletal muscle relaxant properties.
Tolerance, dependence and withdrawal
Abrupt or rapid discontinuation from etizolam, as with benzodiazepines, may result in the appearance
of the benzodiazepine withdrawal syndrome, including rebound insomnia.[10]Neuroleptic malignant
syndrome, a rare event in benzodiazepine withdrawal, has been documented in a case of abrupt
withdrawal from etizolam. This is particularly relevant given etizolams short half life relative to
benzodiazepines such as diazepam resulting in a more rapid drug level decrease in blood plasma levels.
In a study that compared the effectiveness of etizolam, alprazolam, and bromazepam for the
treatment of generalized anxiety disorder, all three drugs retained their effectiveness over 2 weeks,
but etizolam became more effective from 2 weeks to 4 weeks, a type of reverse tolerance.[13]
Administering .5 mg etizolam twice daily did not induce cognitive deficits over 3 weeks when
compared to placebo.
When multiple doses of etizolam, or lorazepam, were administered to rat neurons, lorazepam caused
downregulation of alpha-1 benzodiazepine binding sites (tolerance/dependence), while etizolam caused
an increase in alpha-2 benzodiazepine binding sites (reverse tolerance to anti-anxiety effects).[15]
Tolerance to the anticonvulsant effects of lorazepam was observed, but no significant tolerance to
the anticonvulsant effects of etizolam was observed.[15]Etizolam therefore has a reduced liability to
induce tolerance, and dependence, compared with classic benzodiazepines.[15]
Pharmacology
Etizolam, a thienodiazepine derivative, is absorbed fairly rapidly, with peak plasma levels achieved between 30 minutes and 2 hours. It has a mean elimination half life of about 3.5 hours. Etizolam possessespotent hypnotic properties,and is comparable with other short-actingbenzodiazepines.Etizolam acts as afull agonist at the benzodiazepine receptor to produce its range of therapeutic and adverse effects.[18]According to the Italian P.I. sheet[citation needed], etizolam belongs to a new class of diazepines,thienotriazolodiazepines. This new class is easily oxidized, rapidly metabolized, and has a lower risk of accumulation, even after prolonged treatment. Etizolam has an anxiolytic action about 6 times greater than that of diazepam. Etizolam produces, especially at higher dosages, a reduction in time taken to fall asleep,an increase in total sleep time, and a reduction in the number of awakenings. During tests, there were no substantial changes in deep sleep; however, it may reduce REM sleep. In EEG tests of healthy volunteers,etizolam showed some similar characteristics to tricyclic antidepressants.
Our promise:
1. Good quality product and reasonable price~ make customers happy
and save customers money
2. Delivery product on time~ save customers time
3. Professional packing~let the customers receive it successfully
4. Many payment instruments~convenient to pay
5. Service customers forever~ to establish long-term cooperation
relationship
We may do not show all the products for you, please feel free contact
with us for any requirements, we are always here for you, thanks in
advance.
2 contact us:
3. Superiority
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
3,We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.
4. company:
Our company is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and intermediates. It has trade with other Asian countries and Europe, the Americas and African countries. Important exporters of pharmaceutical chemical raw materials and the worlds latest importers of pharmaceutical raw materials.
Our company has always been adhering to the company to market-oriented, customer-centric, with professional and enterprising team spirit and the companys strong financial strength, to provide customers with fast, high quality and efficient services, and always " To benefit customers "for the purpose.
5.F.A.Q:
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1. How is the quality
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The qualities of most products are above 99% purity, same are 99.5% purity.
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2, How is the package
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Foil bag or as customers required.
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| 3.How is the storage |
Keep in dry and cool place.
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4, Do I need to pay extra for shipping cost
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No, our price includes the shipping cost already; you need not pay for any tax and others.
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5, Can I order sample to test
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Yes, you are welcome to order sample before placing bulk order. We will send the sample directly to your door by courier.
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6, minimum quantity
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Usually our minimum quantity is 50g. But you are welcome to order samples to check the quality and our service.
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6. photos: .
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Etizolam Intermediate Pharmaceutical Products C17H15ClN4S Formula SGS Certificat Images |
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