Taxus Chinensis Extract Paclitaxel Post Cycle Therapy Steroids CAS 33069-62-4

Taxus Chinensis Extract Paclitaxel 33069-62-4 for Anti-cancer

1.Description of Paclitax
Paclitax is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.Paclitax is classified as a "plant alkaloid," a "taxane" and an "antimicrotubule agent."
Paclitax use is generally associated with manageable toxicity. Neutropenia and peripheral neuropathy are common clinical side effects of paclitax,The most common dose-limiting toxicity of paclitax, neutropenia, is both dose- and schedule-dependent. Severe neutropenia is typically of short duration and rarely associated with other hematologic toxicities. Cumulative peripheral neurotoxicity is typically mild and often reversible. Hypersensitivity reactions are almost completely prevented by the use of a premedication regimen consisting of corticosteroids, cimetidine or ranitidine, and diphenhydramine.
Paclitaxl is an injectable medication thats infused into your vein. Its used to treat certain types of cancers, including ovarian, breast, and lung cancers and Kaposis sarcoma.Paclitaxel has emerged as an important agent in the treatment of breast cancer. The efficacy and tolerability of this agent, as well as its lack of cross-resistance with anthracyclines, have spurred intensive clinical investigation worldwide.

2.Quick Details:
Products Name:Paclitaxl,Taxo,Onxa
Synonyms: N-BENZYL-BETA-PHENYLISOSERINE ESTER
CAS: 33069-62-4
MF: C47H51NO14
MW: 853.91
EINECS: 205-285-7
Test method: HPLC
Assy(potency): >99%
Residue on ignition: <1%
Appearance: White powder
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3.How Paclitax Works:
Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. "Normal" cells stop dividing when they come into contact with like cells, a mechanism known as contact inhibition. Cancerous cells lose this ability. Cancer cells no longer have the normal checks and balances in place that control and limit cell division. The process of cell division, whether normal or cancerous cells, is through the cell cycle. The cell cycle goes from the resting phase, through active growing phases, and then to mitosis (division).
Paclitax belongs to a class of chemotherapy drugs called plant alkaloids,Plant alkaloids are made from plants. The vinca alkaloids are made from the periwinkle plant (catharanthus rosea). The taxanes are made from the bark of the Pacific Yew tree (taxus). The vinca alkaloids and taxanes are also known as antimicrotubule agents. The podophyllotoxins are derived from the May Apple plant. Camptothecan analogs are derived from the Asian "Happy Tree" (Camptotheca acuminata). Podophyllotoxins and camptothecan analogs are also known as topoisomerase inhibitors. The plant alkaloids are cell-cycle specific. This means they attack the cells during various phases of division.

4.How to Take Paclitax (Dosage)
Injectable Solution:
Your doctor will determine a dose thats right for you based on your individual needs. Your general health may affect your dose. Tell your doctor about all health conditions you have before your doctor or nurse administers the drug to you.
Your dose is determined by your body surface area and the type of cancer that youe being treated for. Body surface area is calculated using your height and weight, so your dose is individualized for you.
the drug may be used as a single agent, as sequential therapy, or in combination with other chemotherapy agents and immunologic agents. Therapy on weekly and every-three-week schedules has been effective.

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